Looking for some fun, Brooke and Peyton crash a college party, but things turn ugly when one of the guys in the dorm drugs Peyton.After Brooke calls Lucas for help, the two bond while caring for a sleeping Peyton, prompting Lucas to look at Brooke in a new light.
The season concluded on May 11, 2004, after 22 episodes.
The wedge between Nathan and Peyton continues to grow after Peyton tires of Nathan's jabs at Lucas.
Meanwhile, Keith forces Karen to deal with her feelings for Dan after she refuses to set foot in the high school gym to support her son.
Lucas asks Keith to play with him in the annual "Father and Son" basketball game, and realizes he got the better father figure after Dan publicly humiliates Nathan on the court.
Meanwhile, Peyton turns down Nathan’s attempts to make up; she is having a hard time dealing with the anniversary of her mother's death and finds a comforting ally in Whitey.